J B Chemicals and Pharmaceuticals Ltd

Nintabid 100mg Capsule

Nintabid 100mg Capsule contains Nintedanib 100 mg, an anti-fibrotic medicine prescribed for the treatment of Idiopathic Pulmonary Fibrosis (IPF), chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype, and certain cases of systemic sclerosis-associated interstitial lung disease (SSc-ILD). It helps slow the progression of lung scarring, preserves lung function, and improves long-term disease management when taken under the supervision of a healthcare professional.

Category: Anti-Fibrotic Medicines

Salt Composition: Nintedanib 100 mg

Manufacturer: J B Chemicals and Pharmaceuticals Ltd

Unit: capsule
Pack Size: 10 Capsules
$906.00

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Overview

Nintedanib works by blocking multiple tyrosine kinase receptors involved in inflammation and fibrosis. By reducing the activity of these pathways, it slows the formation of scar tissue in the lungs. Patients taking Nintabid 100mg Capsule often experience slower disease progression when the medicine is used consistently as prescribed by their pulmonologist.

For the best results, Nintabid 100mg Capsule should be taken with food and at the same time every day. Treatment should not be stopped without medical advice, even if symptoms appear stable. Regular monitoring of liver function and overall health is recommended during therapy.

If you are looking for similar medicines used in respiratory care, you may also explore Nintabid 150mg Capsule through our Respiratory Care Medicines category.

For detailed clinical information about Nintedanib, you can refer to the National Center for Biotechnology Information (NCBI) and the European Medicines Agency (EMA).

Medical Uses & Benefits

Doctors prescribe Nintabid 100mg Capsule for:

  • Idiopathic Pulmonary Fibrosis (IPF)
  • Progressive Fibrosing Interstitial Lung Disease (PF-ILD)
  • Chronic Fibrosing Interstitial Lung Disease
  • Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD)
  • Long-term management of progressive lung fibrosis
  • Slowing deterioration of lung function
  • Patients requiring anti-fibrotic therapy as advised by a pulmonologist

Nintabid 100mg Capsule offers several important benefits for patients with chronic fibrosing lung diseases:

  • Helps slow the progression of Idiopathic Pulmonary Fibrosis (IPF).
  • Reduces the rate of lung function decline.
  • Helps preserve breathing capacity over time.
  • Supports long-term management of progressive interstitial lung diseases.
  • Delays worsening of lung scarring.
  • May reduce the frequency of disease progression events.
  • Improves disease stability when used regularly.
  • Suitable for long-term treatment under specialist supervision.
  • Can help maintain daily physical activity for longer.
  • Recommended by specialists as part of evidence-based IPF management.

Possible Side Effects

Like all medicines, Nintabid may cause side effects, although not everyone experiences them.

Common Side Effects

  • Diarrhea
  • Nausea
  • Vomiting
  • Abdominal pain
  • Loss of appetite
  • Weight loss
  • Increased liver enzymes
  • Fatigue
  • Indigestion
  • Headache
  • Less Common but Serious Side Effects

  • Liver problems
  • Severe diarrhea causing dehydration
  • Bleeding complications
  • Blood clots
  • Gastrointestinal perforation (rare)
  • High blood pressure
  • Allergic reactions
  • Seek immediate medical attention if you notice yellowing of the eyes, severe abdominal pain, blood in stools, chest pain, difficulty breathing, or persistent vomiting.

Directions for Use

  • Take the capsule exactly as prescribed by your doctor.
  • Swallow it whole with a glass of water.
  • Do not crush, chew, or open the capsule.
  • Always take it with food to reduce stomach-related side effects.
  • Try to take it at the same times each day.
  • Continue treatment regularly unless your doctor advises otherwise.
  • If vomiting occurs after taking the dose, do not take an extra capsule; wait until your next scheduled dose.

The dosage is decided by the treating specialist based on the patient's condition and response to treatment.

  • Usually taken twice daily with food.
  • Follow your prescribed dosing schedule strictly.
  • Never increase or decrease the dose on your own.
  • Dose adjustment may be required if significant side effects occur.
  • Missed doses should not be doubled.

How This Medicine Works

Nintabid 100mg Capsule contains Nintedanib, an anti-fibrotic medicine that helps slow the progression of chronic lung diseases characterized by fibrosis (scarring). It works by inhibiting multiple receptor tyrosine kinases, including platelet-derived growth factor (PDGF), fibroblast growth factor (FGF), and vascular endothelial growth factor (VEGF) receptors.

These signaling pathways play a key role in inflammation, abnormal tissue repair, and scar formation. By blocking them, Nintedanib reduces the activity of fibroblasts—the cells responsible for producing excess scar tissue. This helps slow further damage to lung tissue and preserves lung function over time.

Although Nintabid does not reverse existing lung scarring or cure the disease, regular treatment can significantly delay disease progression and help patients maintain their quality of life for longer.

For patients requiring a higher strength, you may also explore Nintabid 150mg Capsule on your website (Internal Link).

Safety Information

  • Prescription medicine—use only under medical supervision.
  • Liver function tests should be monitored before and during treatment.
  • Inform your doctor if you have liver disease, bleeding disorders, or heart disease.
  • Avoid pregnancy during treatment and use effective contraception.
  • Breastfeeding is generally not recommended while taking Nintedanib.
  • Inform your doctor about all medicines, vitamins, and herbal supplements you are taking.
  • Avoid smoking, as it may reduce treatment effectiveness.
  • Stay well hydrated, especially if diarrhea develops.
  • Do not discontinue treatment without consulting your healthcare provider.

Missed Dose Instructions

  • Take the missed dose as soon as you remember.
  • If it is almost time for your next scheduled dose, skip the missed dose.
  • Do not take two capsules together to make up for a forgotten dose.
  • Never take extra medicine without consulting your doctor.
  • Continue your regular dosing schedule thereafter.

Available Substitutes

Substitutes should only be used after approval from your treating pulmonologist.

Possible alternatives containing Nintedanib include:

  • Nintib 100mg Capsule
  • Nindanix 100mg Capsule
  • Nindanib 100mg Capsule
  • Nintedanib 100mg Capsules (various approved manufacturers)

Availability may vary depending on your location and prescription requirements.

Important Usage Tips

  • Always take the capsule with food.
  • Swallow it whole with water.
  • Do not chew, crush, or open the capsule.
  • Maintain the same dosing schedule every day.
  • Drink plenty of fluids, especially if diarrhea develops.
  • Attend regular follow-up appointments.
  • Liver function tests should be performed as advised.
  • Inform your doctor if you notice yellowing of the eyes, unusual bleeding, severe diarrhea, or persistent vomiting.
  • Avoid smoking, as it may worsen lung disease.
  • Continue treatment even if you feel well, unless instructed otherwise by your doctor.

Key Facts

  • Medicine Type: Anti-fibrotic Agent
  • Active Ingredient: Nintedanib
  • Prescription Required: Yes
  • Dosage Form: Capsule
  • Route of Administration: Oral
  • Suitable For: Adults only
  • Habit Forming: No
  • Pregnancy: Use only if clearly prescribed; generally avoided.
  • Breastfeeding: Usually not recommended.
  • Alcohol: Ask your doctor, especially if you have liver disease.
  • Driving: Usually does not impair driving ability, but dizziness may occur in some patients.

Drug Interactions

Inform your healthcare provider about all medicines you are taking.

Nintabid may interact with:

  • Warfarin and other blood thinners
  • Aspirin
  • Clopidogrel
  • Ketoconazole
  • Rifampicin
  • Erythromycin
  • Carbamazepine
  • Phenytoin
  • St. John's Wort
  • Certain chemotherapy medicines
  • Immunosuppressants
  • Other medicines affecting liver enzymes
  • These interactions may increase the risk of bleeding, alter drug levels, or increase side effects.

Patient Concerns & Guidance

Can Nintabid cure pulmonary fibrosis?

No. It does not cure pulmonary fibrosis but helps slow the progression of lung scarring.

How long should I continue treatment?

Treatment duration depends on your doctor's assessment. Many patients continue therapy for months or years.

Can diarrhea occur?

Yes. Diarrhea is one of the most common side effects. Stay hydrated and inform your doctor if it becomes severe.

Will I need blood tests?

Yes. Liver function tests and routine monitoring are usually recommended during treatment.

Can elderly patients take this medicine?

Yes, but they may require closer monitoring depending on their overall health.

Is smoking allowed?

Smoking may reduce treatment effectiveness and worsen lung disease. Quitting smoking is strongly advised.

Can I stop taking it if I feel better?

No. Do not stop treatment unless your doctor instructs you to do so.

FAQs

1. What is Nintabid 100mg Capsule used for?

It is used to slow the progression of Idiopathic Pulmonary Fibrosis (IPF), Progressive Fibrosing Interstitial Lung Disease (PF-ILD), and Systemic Sclerosis-Associated ILD.

2. How does Nintabid work?

It blocks proteins involved in lung fibrosis, helping reduce further scar tissue formation.

3. Can it cure pulmonary fibrosis?

No. It helps slow disease progression but does not cure existing lung damage.

4. Should I take it with food?

Yes. Taking it with meals helps reduce stomach-related side effects.

5. What happens if I miss a dose?

Skip the missed dose if the next dose is near. Never double the dose.

6. Is diarrhea common?

Yes. It is one of the most frequently reported side effects.

Ingredients

Each hard gelatin capsule contains:

  • Nintedanib 100 mg
  • Microcrystalline Cellulose
  • Colloidal Silicon Dioxide
  • Magnesium Stearate
  • Capsule Shell Ingredients
  • Approved pharmaceutical excipients

Storage

  • Store below 30°C.
  • Keep in the original packaging.
  • Protect from moisture and direct sunlight.
  • Keep away from children and pets.
  • Do not use after the expiry date.
  • Dispose of unused medicine safely according to pharmacist instructions.

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Disclaimer: The information provided on this page is for general informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or qualified health provider with any questions regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.