Nintabid 150 mg Capsule

Nintabid 150 mg Capsule is a prescription medicine containing Nintedanib 150 mg, an anti-fibrotic and tyrosine kinase inhibitor used in the treatment of various progressive fibrosing lung diseases. It is primarily indicated for Idiopathic Pulmonary Fibrosis (IPF), chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype, and systemic sclerosis-associated interstitial lung disease (SSc-ILD).

Nintedanib works by blocking multiple pathways responsible for fibrosis and abnormal tissue scarring inside the lungs. By slowing the formation of scar tissue, it helps preserve lung function and reduces the rate at which breathing ability declines. Although it does not cure lung fibrosis, regular treatment can help slow disease progression and improve long-term disease management.

The capsule should be taken exactly as prescribed by the physician, preferably with food, and swallowed whole with water. Patients should not crush, chew, or open the capsule. Routine monitoring of liver function and overall health may be required during treatment.

• Idiopathic Pulmonary Fibrosis (IPF)
• Progressive Fibrosing Interstitial Lung Disease (PF-ILD)
• Chronic Fibrosing Interstitial Lung Disease
• Systemic Sclerosis-associated Interstitial Lung Disease (SSc-ILD)

• Helps slow the progression of Idiopathic Pulmonary Fibrosis (IPF).
• Preserves lung function for a longer duration.
• Reduces the rate of decline in forced vital capacity (FVC).
• Helps manage chronic progressive fibrosing interstitial lung diseases.
• Effective in systemic sclerosis-associated interstitial lung disease.
• Targets the underlying fibrosis process rather than only symptoms.
• May improve long-term disease management when used consistently.
• Clinically proven anti-fibrotic therapy.
• Helps delay worsening of breathing difficulties.
• Supports improved quality of life under regular medical supervision.

Common side effects may include:

• Diarrhea
• Nausea
• Vomiting
• Abdominal pain
• Loss of appetite
• Weight loss
• Elevated liver enzymes
• Fatigue
• Headache
• Indigestion

Seek immediate medical attention if you experience severe diarrhea, persistent vomiting, signs of liver problems (yellow eyes or skin), chest pain, severe bleeding, or allergic reactions.

• Take exactly as prescribed by your doctor.
• Swallow the capsule whole with water.
• Do not crush, chew, or open the capsule.
• Take with food to reduce stomach discomfort.
• Take it at the same time every day.
• Continue treatment unless advised otherwise by your healthcare provider.
• Do not alter the dose without medical advice.

The usual recommended dose for adults is 150 mg twice daily, approximately 12 hours apart, or as directed by the treating physician. Dosage adjustments may be required based on tolerance, liver function, or side effects. Never self-adjust the dose.

Nintedanib is a multiple tyrosine kinase inhibitor that blocks receptors involved in fibrosis, including platelet-derived growth factor (PDGF), fibroblast growth factor (FGF), and vascular endothelial growth factor (VEGF) receptors. By inhibiting these signaling pathways, it slows fibroblast activation and reduces excessive scar tissue formation in the lungs. This helps preserve lung function and slows disease progression in fibrosing lung diseases.

• Prescription medicine; use only under medical supervision.
• Liver function should be monitored during treatment.
• Not recommended during pregnancy.
• Effective contraception is advised during treatment.
• Breastfeeding is generally not recommended.
• Inform your doctor about liver disease or bleeding disorders.
• Use cautiously in patients receiving anticoagulants.
• Avoid smoking as it may reduce treatment effectiveness.
• Inform your physician before any surgery.
• Keep all follow-up appointments for monitoring.

If you miss a dose, skip the missed dose and take your next scheduled dose at the usual time. Do not take two doses together to make up for the missed dose.

(Containing Nintedanib 150 mg)

• Nindanib 150 mg Capsule
• Nintedanib 150 mg Capsule
• Nindanix 150 mg Capsule
• Nintib 150 mg Capsule
• Other Nintedanib 150 mg brands as prescribed by the physician

• Always take with food.
• Swallow whole without opening.
• Drink adequate fluids if diarrhea occurs.
• Attend regular liver function tests.
• Report unusual bleeding immediately.
• Avoid pregnancy during treatment.
• Inform your doctor about all medicines you take.
• Avoid missing doses.
• Follow the prescribed schedule strictly.
• Continue therapy even if symptoms improve unless advised otherwise.

• Contains Nintedanib 150 mg.
• Anti-fibrotic medicine.
• Prescription-only medication.
• Used in progressive lung fibrosis.
• Helps slow lung function decline.
• Does not cure fibrosis but slows progression.
• Requires regular medical monitoring.
• Usually taken twice daily with food.

Inform your doctor if you are taking:

• Blood thinners (Warfarin, Apixaban, Rivaroxaban)
• Aspirin or NSAIDs
• Rifampicin
• Ketoconazole
• Erythromycin
• Clarithromycin
• Carbamazepine
• Phenytoin
• St. John's Wort
• Other prescription medicines or herbal supplements

Patients with progressive lung fibrosis often experience increasing breathlessness and reduced exercise tolerance. Nintabid helps slow further lung damage but should be taken consistently for maximum benefit. Follow a healthy lifestyle, avoid smoking, attend regular follow-up visits, undergo liver function monitoring, and promptly report severe diarrhea, unusual bleeding, chest pain, or symptoms of liver injury.

1. What is Nintabid 150 mg Capsule used for?

It is used to treat Idiopathic Pulmonary Fibrosis, progressive fibrosing interstitial lung disease, and systemic sclerosis-associated interstitial lung disease.

2. Does it cure pulmonary fibrosis?

No. It helps slow disease progression but does not cure pulmonary fibrosis.

3. Should it be taken with food?

Yes. It should always be taken with food to reduce stomach-related side effects.

4. Can the capsule be opened?

No. Swallow it whole without crushing, chewing, or opening.

5. What is the most common side effect?

Diarrhea is the most commonly reported side effect.

6. Is regular monitoring required?

Yes. Liver function tests and routine follow-up are recommended.

7. Can pregnant women use this medicine?

No. It is generally not recommended during pregnancy.

8. What should I do if severe diarrhea occurs?

Contact your doctor immediately, as treatment adjustments may be required.

9. Can smokers take this medicine?

Smoking may reduce treatment effectiveness. Patients are advised to stop smoking.

Each hard capsule contains:

• Nintedanib 150 mg

Inactive ingredients may include approved pharmaceutical excipients used in capsule formulation.

• Store below 30°C.
• Protect from moisture and direct sunlight.
• Keep in the original blister pack until use.
• Keep out of reach of children.
• Do not use after the expiry date.